Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dynamic nanostructures at the surface of rising bubbles in amphiphile solutions: Comparison of low-molecular-weight surfactants and proteins.

Advances in colloid and interface science·2025

Same author

Experimental and theoretical study of adsorption of synthesized amino acid core derived surfactants at an air/water interface.

Physical chemistry chemical physics : PCCP·2022

Same author

Nanocomposite multifunctional polyelectrolyte thin films with copper nanoparticles as the antimicrobial coatings.

Colloids and surfaces. B, Biointerfaces·2019

Same author

Interfacial and structural characteristics of polyelectrolyte multilayers used as cushions for supported lipid bilayers.

Soft matter·2017

Same author

Gadolinium alginate nanogels for theranostic applications.

Colloids and surfaces. B, Biointerfaces·2017

Same author

High Frequency of Arterial Hypertension in Patients After Liver Transplantation.

Transplantation proceedings·2016

Search research articles

Related Experiment Video

Updated: May 27, 2026

Compact Quantum Dots for Single-molecule Imaging

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

Polyelectrolyte multilayer capsules with quantum dots for biomedical applications.

M Adamczak¹, H J Hoel, G Gaudernack

¹Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Krakow, Poland. ncmadamc@cyf-kr.edu.pl

Colloids and Surfaces. B, Biointerfaces

|November 15, 2011

Summary

This summary is machine-generated.

This study successfully encapsulated cadmium telluride (CdTe) quantum dots within polyelectrolyte nanocapsules using layer-by-layer adsorption. The resulting nanocapsules show potential for various applications, with initial cytotoxicity assessments indicating good biocompatibility.

More Related Videos

Production and Targeting of Monovalent Quantum Dots

Production and Targeting of Monovalent Quantum Dots

Published on: October 23, 2014

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications

Published on: February 6, 2016

Related Experiment Videos

Last Updated: May 27, 2026

Compact Quantum Dots for Single-molecule Imaging

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

Production and Targeting of Monovalent Quantum Dots

Production and Targeting of Monovalent Quantum Dots

Published on: October 23, 2014

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications

Published on: February 6, 2016

Area of Science:

Materials Science
Nanotechnology
Biotechnology

Background:

Quantum dots (QDs) offer unique optical properties but require stable encapsulation for applications.
Polyelectrolyte layer-by-layer assembly is a versatile method for creating nanoscale capsules.
Biocompatible materials are crucial for biomedical applications of nanomaterials.

Purpose of the Study:

To encapsulate cadmium telluride (CdTe) quantum dots within polyelectrolyte nanocapsules.
To investigate the formation and characterization of these nanocapsules using different polyelectrolyte pairs.
To assess the preliminary cytotoxicity of the fabricated nanocapsules.

Main Methods:

Layer-by-layer adsorption of polyelectrolytes (PAH/PSS and PLys/PGA) to form nanocapsule shells around CdTe QDs.
Electrophoretic mobility and light scattering for zeta potential and size measurements.
Spectrofluorimetry, atomic force microscopy (AFM), and flow cytometry for characterization and cytotoxicity assessment.

Main Results:

Successful formation of polyelectrolyte nanocapsules encapsulating CdTe QDs.
Characterization confirmed shell growth, size, and optical properties of encapsulated QDs.
Preliminary flow cytometry results indicated low cytotoxicity on B-lymphoblastoid and mononuclear cells.

Conclusions:

Polyelectrolyte nanocapsules effectively encapsulate CdTe QDs.
The layer-by-layer method provides control over nanocapsule properties.
Encapsulated QDs exhibit stable fluorescence and low cytotoxicity, suggesting potential for biomedical imaging or sensing.