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Updated: May 27, 2026

The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia
Published on: November 19, 2008
Nosology: infarction hematoma, a placental infarction encasing a hematoma
1Department of Pathology, University of Louisville, Kosair Childrens Hospital, Louisville, KY 40202, USA. Robert.Bendon@Nortonhealthcare.org
Six cases of mothers whose placentas demonstrate multiple infarctions with a central intraparenchymal hematoma are presented. The histology is distinct from intervillous thrombus and Kline hemorrhage. The mothers have a history of multiple fetal losses, eclampsia/preeclampsia, and at least 1 case of documented recurrence. A distinct name is proposed for this lesion, infarction hematoma, which would help clarify further studies.
Six cases of mothers whose placentas demonstrate multiple infarctions with a central intraparenchymal hematoma are presented. The histology is distinct from intervillous thrombus and Kline hemorrhage. The mothers have a history of multiple fetal losses, eclampsia/preeclampsia, and at least 1 case of documented recurrence. A distinct name is proposed for this lesion, infarction hematoma, which would help clarify further studies.
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