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Updated: May 27, 2026

Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies
Published on: November 27, 2013
Dynamic control of gold nanoparticle morphology in a microchannel flow reactor by glucose reduction in aqueous sodium
Takayuki Ishizaka1, Atsushi Ishigaki, Hajime Kawanami
1Research Center for Compact Chemical System, National Institute of Advanced Industrial Science and Technology (AIST), 4-2-1 Nigatake, Sendai 983-8551, Japan. t-ishizaka@aist.go.jp
Abstract:
Continuous flow synthesis of gold nanoparticles was demonstrated using a microchannel reactor with glucose reduction in aqueous alkaline medium. Particle size, morphology, and visual/optical properties of the dispersion liquid were controlled dynamically by tuning of the rate of NaOH addition. Characteristic star-like nanoparticles formed spontaneously as a quasi-stable state, but they changed the morphology to round shape and showed spectral change over time.

