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A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
Published on: May 6, 2018
Osteoblastic osteosarcoma in a Grey Mouse Lemur (Microcebus murinus) - short communication
Mátyás Liptovszky1, Edina Perge, Viktor Molnár
1Budapest Zoo and Botanical Garden Állatkerti krt. 6-12 H-1146 Budapest Hungary. liptovszky@gmail.com
Acta Veterinaria Hungarica
|November 15, 2011
Summary
This case report details the first known instance of osteosarcoma in a Grey Mouse Lemur (Microcebus murinus). The study documents a rare mandibular tumor in this prosimian species.
Area of Science:
- Veterinary Medicine
- Primatology
- Oncology
Background:
- Grey Mouse Lemurs (Microcebus murinus) are endemic to Madagascar and are abundant in native populations.
- Tumors are common in primates, but neoplasia is infrequently reported in lemurs.
- Osteosarcoma is a rare bone cancer, typically affecting long bones in humans and dogs.
Observation:
- A case of mandibular osteoblastic osteosarcoma in a Grey Mouse Lemur is presented.
- This represents a rare occurrence of neoplasia in the mandible of this lemur species.
- The tumor was identified and characterized through veterinary examination and histopathology.
Findings:
- This is the first documented case of osteosarcoma in a prosimian.
- The study reports the first instance of a mandibular tumor in the Grey Mouse Lemur.
- The findings contribute to the limited literature on neoplasia in lemurs.
Implications:
- Highlights the importance of veterinary surveillance for tumors in non-model primates.
- Provides crucial data for comparative oncology studies between lemurs and other primates.
- Enhances understanding of rare cancer presentations in unique mammalian species.

