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Nocturia in older men.

Boris van Doorn¹, J L H Ruud Bosch

¹Department of Urology, University Medical Center Utrecht, Utrecht, The Netherlands. b.vandoorn@umcutrecht.nl

|November 15, 2011

Summary

Nocturia, or waking to urinate, is common in older men and affects sleep and quality of life. Understanding its causes is key to effective treatment, with desmopressin being a primary option for men under 65.

Area of Science:

Urology
Geriatrics
Sleep Medicine

Background:

Nocturia significantly impacts sleep quality and overall quality of life.
It is a prevalent issue, particularly among the aging male population.
Nocturia can be associated with increased risks of hip fractures and mortality.

Purpose of the Study:

To review the definition, epidemiology, pathophysiology, diagnostics, and treatment of nocturia.
To focus on nocturia management specifically in older men.
To highlight the importance of multifactorial etiology assessment.

Main Methods:

Literature review summarizing existing research on nocturia.
Emphasis on diagnostic tools including frequency-volume charts, patient history, physical examination, and serum analysis.

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Discussion of various treatment modalities, from lifestyle adjustments to pharmacotherapy.

Main Results:

Nocturia is defined as voiding two or more times per night.
Common causes include nocturnal polyuria, 24-hour polyuria, overactive bladder (potentially due to BPH), and sleep disturbances.
Lifestyle adjustments can be helpful; medical therapies like 5-alpha reductase inhibitors, alpha-blockers, or anti-muscarinics show limited efficacy.

Conclusions:

Thorough assessment of nocturia's multifactorial causes is essential for effective management.
Desmopressin is a key medical treatment option but has age restrictions (under 65) due to hyponatremia risk.
Addressing nocturia is crucial for improving sleep, quality of life, and potentially mitigating associated health risks in older men.