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The management of pseudomyxoma peritonei
1Department of Obstetrics and Gynecology, State University of New York, Stony Brook 11794-8091.
Cancer
|October 1, 1990
Summary
Pseudomyxoma peritonei management involves aggressive surgery, often requiring multiple operations. Long-term nutritional support improves survival quality for select patients, as chemotherapy is ineffective.
Area of Science:
- Oncology
- Surgical Oncology
- Gastroenterology
Background:
- Pseudomyxoma peritonei is a rare condition characterized by mucinous ascites.
- Standard treatment involves cytoreductive surgery, which is often extensive.
- Recurrence is common, necessitating repeat surgical interventions.
Purpose of the Study:
- To review the management of patients diagnosed with pseudomyxoma peritonei.
- To evaluate the effectiveness of current treatment modalities.
- To identify factors contributing to improved patient survival and quality of life.
Main Methods:
- Retrospective review of nine patients with pseudomyxoma peritonei.
- Analysis of surgical interventions, including multiple laparotomies.
- Assessment of chemotherapy efficacy and the role of nutritional support.
Main Results:
- Aggressive surgical tumor resection is the cornerstone of pseudomyxoma peritonei management.
- Many patients undergo multiple laparotomies due to disease recurrence.
- Chemotherapy, including cisplatin, demonstrated limited efficacy.
- Long-term nutritional support was associated with enhanced quality of survival in select cases.
Conclusions:
- Pseudomyxoma peritonei management is challenging, often requiring extensive surgical care.
- Current chemotherapy regimens show minimal benefit.
- Nutritional support is a critical component for improving long-term outcomes and quality of life in patients with pseudomyxoma peritonei.
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