Treatment adherence in pediatric eosinophilic gastrointestinal disorders

Kevin A Hommel1, James P Franciosi, Elizabeth A Hente

  • 1Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA. kevin.hommel@cchmc.org

Insights

Treatment adherence in pediatric eosinophilic gastrointestinal disorders (EGID) is complex. About 30% of children with EGID show medication nonadherence, highlighting varied adherence across treatments.

Area of Science:

  • Pediatric Gastroenterology
  • Immunology
  • Allergy

Background:

  • Eosinophilic gastrointestinal disorders (EGID) encompass conditions like eosinophilic esophagitis and gastroenteritis.
  • Effective management of EGID relies heavily on consistent treatment adherence.
  • Understanding adherence patterns is crucial for optimizing patient outcomes.

Purpose of the Study:

  • To investigate treatment adherence rates in children diagnosed with EGID.
  • To identify factors contributing to nonadherence in this pediatric population.

Main Methods:

  • A multimethod, multi-informant approach was used, involving parent reports and electronic monitoring.
  • Participants included children aged 2.5-18 years with EGID and their caregivers.
  • Nonadherence was defined as a cut point of 90% adherence.

Main Results:

  • Medication nonadherence prevalence was found to be 30%.
  • Parent reports indicated 91% adherence, while electronic monitors showed 100% adherence.
  • Tube-feeding adherence was high at 99% ± 3%, with 33% nonadherence to food allergen avoidance.

Conclusions:

  • A significant subset of pediatric EGID patients exhibit nonadherence to treatments.
  • Treatment adherence in EGID is multifaceted, with variations observed across different therapeutic interventions.
  • Further research is needed to address the complexities of adherence in EGID management.
Abstract

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