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Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...

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Related Experiment Video

Updated: May 27, 2026

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)
10:02

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)

Published on: March 12, 2020

ADHDgene: a genetic database for attention deficit hyperactivity disorder.

Liuyan Zhang1, Suhua Chang, Zhao Li

  • 1Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China.

Nucleic Acids Research
|November 15, 2011
PubMed
Summary

Attention deficit hyperactivity disorder (ADHD) is a common psychiatric disorder influenced by multiple genes. The ADHDgene database integrates genetic data, offering a central resource for researchers to explore ADHD

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Using Brain Activation (nir-HEG/Q-EEG) and Execution Measures (CPTs) in a ADHD Assessment Protocol
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Using Brain Activation (nir-HEG/Q-EEG) and Execution Measures (CPTs) in a ADHD Assessment Protocol

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The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
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The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

Related Experiment Videos

Last Updated: May 27, 2026

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)
10:02

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)

Published on: March 12, 2020

Using Brain Activation (nir-HEG/Q-EEG) and Execution Measures (CPTs) in a ADHD Assessment Protocol
13:09

Using Brain Activation (nir-HEG/Q-EEG) and Execution Measures (CPTs) in a ADHD Assessment Protocol

Published on: April 1, 2018

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
05:48

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

Area of Science:

  • Psychiatric Genetics
  • Computational Biology
  • Bioinformatics

Background:

  • Attention deficit hyperactivity disorder (ADHD) affects approximately 5% of the global population, presenting a significant public health challenge.
  • The polygenic nature of ADHD necessitates integrated genetic data for comprehensive analysis and understanding of its complex etiology.
  • Existing genetic research on ADHD is fragmented, lacking a centralized resource for data aggregation and mining.

Purpose of the Study:

  • To develop the ADHDgene database, a centralized, integrated resource for ADHD-related genetic factors.
  • To provide researchers with a unified platform for accessing and analyzing genetic data pertinent to ADHD.
  • To facilitate in-depth data mining and exploration of the genetic underpinnings of ADHD.

Main Methods:

  • Comprehensive literature review to identify and integrate ADHD-related genetic factors.
  • Development of the ADHDgene database, incorporating genetic data and associated information.
  • Implementation of advanced analytical tools, including linkage disequilibrium analysis, pathway-based analysis, and gene mapping.
  • Creation of powerful search functionalities and a graphical browser for intuitive data navigation.

Main Results:

  • Successful development and launch of the ADHDgene database, the first of its kind for ADHD research.
  • Integration of a substantial volume of ADHD-related genetic information from extensive literature review.
  • Provision of functional analysis results, including linkage disequilibrium, pathway analysis, and gene mapping, to offer new insights.
  • Development of user-friendly tools for efficient data retrieval and visualization.

Conclusions:

  • The ADHDgene database serves as a crucial centralized genetic resource and analysis platform for ADHD research.
  • This initiative addresses the need for integrated genetic data, facilitating a deeper understanding of ADHD's genetic complexity.
  • The database and its associated tools are freely available to the research community, promoting collaborative advancements in ADHD genetics.