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Effects of the plant flavonoid baohuoside-1 on cancer cells in vitro
1Department of Child Health, University of Queensland, Mater Children's Hospital, South Brisbane, Australia.
Cancer Letters
|September 1, 1990
Abstract:
The novel plant flavonoid 3,5,7,-trihydroxy-4'-methoxyl-8'-prenylflavone-3-O-alpha-L-rham nopranoxide (designated baohuoside-1) was shown to have cytotoxic and cytostatic effects on 6 cancer cell-lines, by means of microscopy, 51Cr-release and growth inhibition. The IC50 on the cells tested ranged from 2.8 to 7.5 micrograms/ml. At tumouricidal concentrations, inhibition of DNA and RNA synthesis, but not protein synthesis was observed.