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Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents
Published on: August 22, 2025
High-performance sport, marijuana, and cannabimimetics.
1Penrose, Colorado 81240, USA.
Journal of Analytical Toxicology
|November 15, 2011
Summary
The World Anti-Doping Agency prohibits cannabinoids and synthetic cannabinoids due to adverse health effects and performance decrements. This review explains their impact on athletes and sports regulations.
Area of Science:
- Sports Science
- Pharmacology
- Anti-Doping
Background:
- Cannabinoid use in sports is a contentious issue with ongoing debate.
- Adverse health effects and performance decrements associated with cannabinoid use are increasingly documented.
Observation:
- This article reviews cannabinoids and cannabimimetics impacting sports, rules, and athlete performance.
- It explores the history of marijuana in collegiate and Olympic sports.
- Guidelines for adding substances to the World Anti-Doping Agency (WADA) Prohibited List are summarized.
Findings:
- Cannabinoids and synthetic cannabimimetics (e.g., Spice, K2) activate the same receptors as THC.
- Information on the pharmacological effects and mechanisms of action of these substances is updated.
- The rationale behind WADA's prohibition of cannabinoid and cannabimimetic use in competition is presented.
Implications:
- Understanding the impact of cannabinoids on athletes is crucial for maintaining fair play.
- The prohibition aligns with WADA's commitment to athlete health and integrity.
- Continued vigilance and research are necessary to address evolving substance use in sports.
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