Related Experiment Videos
Disseminated tuberculosis presenting as acute coronary syndrome
1Department of Cardiology, Mymensingh Medical College, Mymensingh, Bangladesh. drgobinda@yahoo.com
Mymensingh Medical Journal : MMJ
|November 15, 2011
Summary
Tuberculosis can rarely cause acute myopericarditis, a serious heart inflammation. This case highlights disseminated tuberculosis mimicking acute coronary syndrome in a young man.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Tuberculosis (TB) is a significant public health concern, particularly in Bangladesh.
- While common, TB rarely manifests as acute myopericarditis, a heart inflammation.
Observation:
- A 26-year-old male presented with severe chest pain and prolonged fever.
- Initial investigations revealed ECG changes consistent with acute coronary syndrome (ST elevation), elevated Troponin I, high ESR, and an enlarged cardiac silhouette on chest X-ray.
Findings:
- Echocardiography showed myocardial cavitary lesions and pericardial effusion.
- CT scan confirmed cardiac and pulmonary tuberculous lesions, including calcified cavities within the myocardium and interventricular septum.
Implications:
- This case underscores the importance of considering disseminated tuberculosis in young patients presenting with acute coronary syndrome-like symptoms.
- Prompt diagnosis and combined treatment for both acute coronary syndrome and tuberculosis led to an excellent recovery.
Related Concept Videos
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome III: Diagnostic Studies
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Coronary Artery Disease III: Clinical Manifestations
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...