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Published on: October 11, 2018
COORDINATE DESCENT ALGORITHMS FOR NONCONVEX PENALIZED REGRESSION, WITH APPLICATIONS TO BIOLOGICAL FEATURE SELECTION
1Department of Biostatistics, Department of Statistics, University of Kentucky, 121 Washington Ave., Room 203C, Lexington, Kentucky 40536-0003, USA. Department of Statistics, and Actuarial Sciences, Department of Biostatistics, University of Iowa, 241 Schaeffer Hall, Iowa City, Iowa 52242, USA.
Coordinate descent algorithms offer a faster and more stable approach for variable selection using nonconvex penalties like the minimax concave penalty (MCP) and smoothly clipped absolute deviation (SCAD). These methods are effective alternatives to the lasso, with MCP showing particular promise.
Area of Science:
- Statistics
- Machine Learning
- Computational Statistics
Background:
- Nonconvex penalty functions, such as the smoothly clipped absolute deviation (SCAD) and minimax concave penalty (MCP), offer theoretical advantages for variable selection.
- However, fitting models with these penalties presents challenges, often leading to unstable solutions.
Purpose of the Study:
- To demonstrate the efficacy of coordinate descent algorithms for fitting models with nonconvex penalties.
- To establish the theoretical convergence properties of these algorithms.
- To compare their performance against existing methods.
Main Methods:
- Application of coordinate descent algorithms for model fitting with SCAD and MCP penalties.
- Development and application of convexity diagnostics to identify locally convex regions.
- Comparative analysis with existing variable selection techniques, including the lasso.
Main Results:
- Coordinate descent algorithms provide a stable and significantly faster method for fitting models with nonconvex penalties.
- Convexity diagnostics effectively identify regions of local convexity.
- Simulation studies and data examples show MCP and SCAD as viable alternatives to the lasso, with MCP often being the preferred choice.
Conclusions:
- Coordinate descent algorithms are a powerful tool for variable selection using nonconvex penalties.
- MCP and SCAD, particularly MCP, represent valuable alternatives to the lasso in various applications.
- The integration of convexity diagnostics enhances the reliability of these methods.
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