Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epiphytes, Parasites, and Carnivores02:40

Epiphytes, Parasites, and Carnivores

16.8K
Plants often form mutualistic relationships with soil-dwelling fungi or bacteria to enhance their roots’ nutrient uptake ability. Root-colonizing fungi (e.g., mycorrhizae) increase a plant’s root surface area, which promotes nutrient absorption. While root-colonizing, nitrogen-fixing bacteria (e.g., rhizobia) convert atmospheric nitrogen (N2) into ammonia (NH3), making nitrogen available to plants for various biological functions. For example, nitrogen is essential for the...
16.8K
Lineage Commitment01:21

Lineage Commitment

4.4K
Commitment is the  process whereby stem cells:
4.4K
Epigenetic Regulation01:46

Epigenetic Regulation

33.8K
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
33.8K
Master Transcription Regulators02:23

Master Transcription Regulators

7.8K
Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
7.8K
GTPases and their Regulation02:14

GTPases and their Regulation

9.8K
Guanine nucleotide-binding proteins (G-proteins), also known as GTPases, are a superfamily of proteins that regulate many cellular processes, such as cell signaling, vesicular transport, and the regulation of cell shape and motility. Mutation or dysfunction of these proteins can lead to disease. There are around 40,000 known G-proteins that can broadly be classified into two groups ‒  small G-proteins consisting of a single domain and large multi-domain G-proteins.
Large G-proteins,...
9.8K
Regulated Protein Degradation02:58

Regulated Protein Degradation

8.9K
It is vital to regulate the activity of enzymatic as well as non-enzymatic proteins inside the cell. This can be achieved either through creating a balance between their rate of synthesis and degradation or regulating the intrinsic activity of the protein. Both these regulation mechanisms play an essential role in the normal functioning of cells.
Protein degradation plays two important roles in the cells. It helps to protect cells from misfolded or damaged proteins before they lead to a...
8.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Low-Profile Posterior Lumbar Fusion Combined With Proximal Interlaminar Coflex Dynamic Fixation for Lumbar Degenerative Diseases: A Comparative Study.

Orthopaedic surgery·2026
Same author

The ZFP36/ZFP252-OsDOG1L1-OsPP2Cs module regulates seed germination in rice.

Journal of integrative plant biology·2026
Same author

Expression of miR-27a in Patients with Steroid-associated Femoral Head Osteonecrosis and Its Regulatory Mechanism on Proliferation and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells.

Journal of musculoskeletal & neuronal interactions·2026
Same author

Strength-Toughness-Wear Coupling Mechanisms of Low-Carbon Martensitic Wear-Resistant Steel Enabled by Ti/Nb Microalloying-Driven Carbide Precipitation and Synergistic Regulation of Tempered Microstructures.

Materials (Basel, Switzerland)·2026
Same author

Predicting the prognosis of breast cancer patients by using nutrition-based index: a systematic review and meta-analysis.

Frontiers in oncology·2026
Same author

Risk factors for bone cement leakage in percutaneous vertebroplasty and its prevention.

Pakistan journal of medical sciences·2026

Related Experiment Video

Updated: Feb 2, 2026

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
09:13

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases

Published on: November 22, 2024

1.8K

Gametocytogenesis in malaria parasite: commitment, development and regulation.

Zhenyu Liu1, Jun Miao, Liwang Cui

  • 1Department of Entomology, The Pennsylvania State University, 537 ASI Building University Park, PA 16802, USA.

Future Microbiology
|November 16, 2011
PubMed
Summary

Understanding malaria parasite sexual development is key to transmission control. This review updates knowledge on gametocytogenesis, crucial for developing strategies to eliminate malaria.

More Related Videos

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages
08:23

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Published on: May 30, 2019

12.2K
Protocol for Production of a Genetic Cross of the Rodent Malaria Parasites
13:39

Protocol for Production of a Genetic Cross of the Rodent Malaria Parasites

Published on: January 3, 2011

15.7K

Related Experiment Videos

Last Updated: Feb 2, 2026

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
09:13

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases

Published on: November 22, 2024

1.8K
Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages
08:23

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Published on: May 30, 2019

12.2K
Protocol for Production of a Genetic Cross of the Rodent Malaria Parasites
13:39

Protocol for Production of a Genetic Cross of the Rodent Malaria Parasites

Published on: January 3, 2011

15.7K

Area of Science:

  • Malariology and Parasitology
  • Molecular and Cellular Biology
  • Genetics and Genomics

Background:

  • Malaria parasites exhibit a complex life cycle involving vertebrate and mosquito hosts.
  • Gametocytes, essential for parasite transmission, develop within the vertebrate host.
  • Despite advances, the triggers and mechanisms of sexual development remain poorly understood.

Purpose of the Study:

  • To provide an updated overview of molecular and cellular events in Plasmodium sexual development.
  • To elucidate the regulation of gene expression during gametocytogenesis.
  • To highlight the importance of understanding gametocyte development for malaria control.

Main Methods:

  • Review of recent studies utilizing genome-wide analytical tools.
  • Analysis of genetic manipulation technologies in Plasmodium research.
  • Synthesis of current knowledge on gene expression patterns and molecular distinctions.

Main Results:

  • Significant progress has been made in understanding gene expression patterns during sexual development.
  • Molecular distinctions between sexes and gamete formation mechanisms are increasingly clear.
  • Key triggers and regulatory mechanisms for sexual commitment remain largely elusive.

Conclusions:

  • Understanding the molecular basis of gametocyte development is critical for malaria elimination efforts.
  • Further research into the triggers and regulation of sexual development is needed.
  • Targeting gametocytogenesis offers a promising strategy for interrupting malaria transmission.