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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...

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Related Experiment Video

Updated: May 27, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
10:28

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

Non-FDG PET in oncology.

R Núñez Miller1, M A Pozo

  • 1Department of Nuclear Medicine, MD Anderson Cancer Center, Madrid, Spain. rnps@sbcglobal.net

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
|November 16, 2011
PubMed
Summary

New positron emission tomography (PET) tracers beyond FDG PET/CT offer insights into cancer biology. These non-FDG PET agents are advancing personalized cancer therapy research and clinical applications.

Area of Science:

  • Oncology
  • Nuclear Medicine
  • Molecular Imaging

Background:

  • Fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) and PET/Computed Tomography (CT) are standard in cancer care but have limitations.
  • Research has increasingly focused on novel non-FDG PET tracers over the past 15-20 years.

Purpose of the Study:

  • To review non-FDG PET tracers with high potential for clinical application.
  • To highlight how these tracers can enable personalized cancer therapy.

Main Methods:

  • Literature review of research on non-FDG PET tracers.
  • Analysis of the potential clinical utility of various PET imaging agents.

Main Results:

  • Numerous non-FDG PET tracers are under investigation for assessing specific cancer cell functions.

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A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
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Published on: April 17, 2019

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Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
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A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
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A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice

Published on: April 17, 2019

  • These tracers provide unique biological information crucial for tailored treatments.
  • Conclusions:

    • Non-FDG PET tracers are poised to significantly impact personalized cancer treatment strategies.
    • Several of these advanced imaging agents are expected to see clinical use in the near future.