Related Experiment Video
Updated: May 27, 2026

Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis
Published on: October 13, 2023
Imaging of endometrial pathology
Barton F Lane1, Jade J Wong-You-Cheong
1Department of Diagnostic Radiology, University of Maryland School of Medicine, Baltimore, Maryland, USA. blane@umm.edu
Understanding normal endometrial imaging is key for diagnosing gynecologic conditions. This review covers imaging features of the normal and abnormal endometrium, aiding accurate diagnosis and differentiating mimics.
Area of Science:
- Radiology
- Gynecologic Imaging
- Endometrial Pathology
Background:
- The endometrium undergoes cyclical changes during the menstrual cycle and atrophies post-menopause.
- Accurate interpretation of endometrial imaging requires knowledge of the normal spectrum of appearances.
- Pathologic conditions can mimic normal or abnormal endometrial findings.
Purpose of the Study:
- To review the imaging features of the normal and abnormal endometrium.
- To discuss conditions that may mimic endometrial pathology.
- To emphasize the primary imaging modalities for endometrial evaluation.
Main Methods:
- Review of imaging features of the endometrium.
- Emphasis on ultrasound with sonohysterography and magnetic resonance imaging (MRI).
- Discussion of complementary roles of hysterosalpingography, computed tomography (CT), and 18-fluorodeoxyglucose-positron emission tomography (FDG-PET).
Main Results:
- Detailed description of normal endometrial imaging characteristics across different phases and age groups.
- Illustration of common endometrial pathologies and their characteristic imaging findings.
- Identification of conditions that can simulate endometrial pathology on imaging.
Conclusions:
- Ultrasound with sonohysterography and MRI are the preferred modalities for endometrial evaluation.
- Familiarity with normal endometrial imaging is crucial for accurate diagnosis.
- Awareness of potential mimics improves diagnostic specificity in gynecologic imaging.
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