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Related Concept Videos

Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
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Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

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Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Ascites01:19

Ascites

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Gross Anatomy of the Liver01:17

Gross Anatomy of the Liver

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Appendicitis

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Related Experiment Video

Updated: May 27, 2026

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
04:00

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension

Published on: November 15, 2024

Splenomegaly.

Nicholas F Brown1, Daniel J B Marks, Philip J Smith

  • 1University College London Hospital, London.

British Journal of Hospital Medicine (London, England : 2005)
|November 16, 2011
PubMed
Summary
This summary is machine-generated.

Enlarged spleen (splenomegaly) is often found during physical exams and usually indicates a health problem. If the spleen extends below the left rib cage, it requires medical investigation.

Related Experiment Videos

Last Updated: May 27, 2026

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
04:00

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension

Published on: November 15, 2024

Area of Science:

  • Medicine
  • Clinical Examination

Background:

  • Splenomegaly is a frequent clinical finding.
  • The spleen typically resides within the left costal margin.
  • Palpable spleen often signifies splenomegaly.

Purpose of the Study:

  • To highlight the significance of splenomegaly in clinical assessments.
  • To emphasize the pathological nature of palpable spleens.

Main Methods:

  • Routine abdominal examination to assess spleen size.
  • Clinical palpation to determine if the spleen descends below the left costal margin.

Main Results:

  • A palpable spleen is almost universally indicative of splenomegaly.
  • Splenomegaly is generally a pathological condition.

Conclusions:

  • Palpation of an enlarged spleen warrants further investigation.
  • Splenomegaly is a significant clinical sign requiring medical attention.