Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...

Inflammatory Bowel Disease I: Introduction

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...

Inflammatory Bowel Disease V: Surgical Management

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

Inflammatory Bowel Disease III: Crohn's Disease

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...

Intestinal Obstruction I: Introduction

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...

Intestinal Obstruction II: Pathophysiology

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comment on: Impact of low-pressure pneumoperitoneum and deep neuromuscular blockade on surgeon satisfaction and patient outcomes in laparoscopic cholecystectomy patients: A prospective randomised controlled study.

Journal of minimal access surgery·2025

Same author

The Effect of Participation in Tier 3 Services on the Uptake of Bariatric Surgery.

Obesity surgery·2021

Same author

Laparoscopic resection of a gastrointestinal stromal tumour in a Meckel's diverticulum.

Journal of minimal access surgery·2019

Same author

Can the General Surgeon Use Quilting Sutures to Prevent Seromas Following Abdominal Wall Surgery?

Surgical technology international·2018

Same author

The Many Guises of Endometriosis: Giant Abdominal Wall Endometriosis Masquerading as An Incisional Hernia.

International journal of fertility & sterility·2017

Same author

Port site endometrioma: a rare cause of abdominal wall pain following laparoscopic surgery.

BMJ case reports·2017

Search research articles

Related Experiment Video

Updated: May 27, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Ileo-ileal intussusception from Crohn's ileitis.

Rajaraman Durai¹, Farihah Husain, Tayo Oke

¹Department of Surgery, Queen Elizabeth Hospital, London. dr_durai@yahoo.com

British Journal of Hospital Medicine (London, England : 2005)

|November 16, 2011

Summary

Crohn's disease is an inflammatory bowel disease causing abdominal pain and diarrhea. This case highlights a 33-year-old man with a three-month history of these symptoms.

More Related Videos

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Published on: August 21, 2017

Postoperative Ileus Murine Model

Postoperative Ileus Murine Model

Published on: July 12, 2024

Related Experiment Videos

Last Updated: May 27, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Published on: August 21, 2017

Postoperative Ileus Murine Model

Postoperative Ileus Murine Model

Published on: July 12, 2024

Area of Science:

Gastroenterology
Inflammatory Bowel Disease (IBD) research

Background:

Crohn's disease is a chronic inflammatory condition affecting the digestive tract.
Symptoms often include abdominal pain and diarrhea, impacting patient quality of life.

Observation:

A 33-year-old male patient presented with specific symptoms.
The patient reported a three-month history of recurrent abdominal pain.
Occasional diarrhea was also a noted symptom.

Findings:

The presented symptoms are consistent with potential Crohn's disease diagnosis.
Recurrent abdominal pain and diarrhea are key indicators in Crohn's disease presentation.

Implications:

Early recognition of these symptoms is crucial for timely Crohn's disease diagnosis.
Further investigation is warranted to confirm Crohn's disease and initiate appropriate management.
Understanding symptom patterns aids in differentiating Crohn's disease from other gastrointestinal disorders.