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Related Experiment Video

Updated: May 27, 2026

Retzius-Sparing Robot-Assisted Radical Prostatectomy
12:10

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

Cause-specific mortality following radical prostatectomy.

S Shikanov1, M Kocherginsky, A L Shalhav

  • 1Section of Urology, Department of Surgery, University of Chicago, Chicago, IL, USA.

Prostate Cancer and Prostatic Diseases
|November 16, 2011
PubMed
Summary

Radical prostatectomy (RP) patients face higher mortality from other diseases than prostate cancer. Focus on preventing and treating cardiovascular disease and other cancers post-surgery.

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Published on: March 6, 2018

Area of Science:

  • Urology
  • Oncology
  • Public Health

Background:

  • Radical prostatectomy (RP) is a common treatment for localized prostate cancer.
  • Assessing long-term survival requires accounting for competing causes of death.

Purpose of the Study:

  • To evaluate cause-specific mortality after RP in a US population.
  • To adjust for competing risks in mortality analysis.

Main Methods:

  • Utilized the Surveillance, Epidemiology and End Results (SEER) database.
  • Identified 120,392 men undergoing RP for prostate cancer (1988-2003).
  • Analyzed cause-specific mortality data through 2006 using competing risks methods.

Main Results:

  • 15-year prostate cancer mortality was 5.3%, while non-prostate cancer mortality was 30.6%.
  • Cardiovascular disease (11%), other cancers (9.1%), and other causes (10.5%) were leading non-cancer causes of death.
  • Older men (≥65 years) had higher non-prostate cancer mortality (40.8%).

Conclusions:

  • Mortality from cardiovascular disease, other cancers, and other causes exceeds prostate cancer death post-RP.
  • Emphasizes the need for comprehensive health management, including prevention and treatment of non-cancerous conditions in prostate cancer patients.