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Related Concept Videos

Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications

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Related Experiment Video

Updated: May 27, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

[Tailored therapy for rheumatic disease within reach].

Lisa G M van Baarsen1, Beatrijs M Lodde, Paul P Tak

  • 1Academisch Medisch Centrum, afd. Klinische Immunologie en Reumatologie, Amsterdam, the Netherlands. p.p.tak@amc.uva.nl

Nederlands Tijdschrift Voor Geneeskunde
|November 17, 2011
PubMed
Summary

Personalised medicine offers tailored treatments for better effectiveness and fewer side effects. Identifying biomarkers for rheumatoid arthritis (RA) and other immune-mediated diseases is key to optimizing patient response.

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An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
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An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

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Last Updated: May 27, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
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Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

Area of Science:

  • Biomedical science
  • Pharmacogenomics
  • Immunology

Context:

  • Personalised medicine is revolutionizing oncology by tailoring treatments based on genetic biomarkers and tumor characteristics.
  • Rheumatoid arthritis (RA) serves as a potential model for applying personalised medicine principles to immune-mediated inflammatory diseases.
  • Current novel treatments for RA can halt disease progression, but patient response varies significantly.

Purpose:

  • To explore the potential of personalised medicine in immune-mediated inflammatory diseases, using rheumatoid arthritis as a prototype.
  • To highlight the need for patient stratification in RA treatment based on predictive biomarkers.
  • To discuss the future development of tailored therapies for various diseases.

Summary:

  • Personalised medicine aims to enhance therapeutic effectiveness, minimize side effects, and reduce healthcare costs.
  • The abstract discusses the successful application of personalised medicine in oncology and its potential for immune-mediated inflammatory diseases like RA.
  • Identifying biomarkers predictive of treatment response is crucial for stratifying RA patients and optimizing therapeutic outcomes.

Impact:

  • Personalised medicine can lead to more effective and safer treatments for patients with immune-mediated inflammatory diseases.
  • Biomarker discovery will enable precise patient stratification, improving treatment efficacy in RA and other conditions.
  • This approach promises to transform the management of complex diseases by enabling tailored therapeutic strategies.