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OmniMapFree: a unified tool to visualise and explore sequenced genomes
John Antoniw1, Andrew M Beacham, Thomas K Baldwin
1Centre for Sustainable Pest and Disease Management, Rothamsted Research, Harpenden, Herts, AL5 2JQ, UK. john.antoniw@rothamsted.ac.uk
BMC Bioinformatics
|November 17, 2011
Summary
OmniMapFree is a versatile software tool that integrates diverse genomic datasets for comprehensive single genome exploration. It allows researchers to visualize and analyze various data types, enhancing understanding of organismal biology.
Area of Science:
- Genomics
- Bioinformatics
- Computational Biology
Background:
- Whole genome sequencing is a routine approach in species research.
- Current genome browsers typically display limited data types like DNA sequence and annotations.
- Much experimental data remains unintegrated and unsearchable within the whole genome context.
Purpose of the Study:
- To develop a unified software for comprehensive single genome analysis.
- To enable visualization and integration of diverse experimental datasets onto the genome.
Main Methods:
- Developed generic software for viewing entire genomes (chromosome or supercontig context).
- Allows display of genomes at any scale with user-defined features.
- Integrates various data types from classical genetics, transcriptomics, proteomics, and advanced annotation.
Main Results:
- Software enables overlapping and retrieving combined data types at desired scales.
- Generated displays are of publication quality.
- Facilitates follow-up analyses by integrating disparate datasets.
Conclusions:
- OmniMapFree offers a unified, versatile, and user-friendly platform.
- It supports the study of a single genome alongside all available datasets and data types.
- Enhances genomic research by providing a comprehensive analytical tool.
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