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Updated: May 27, 2026
10:13
A Multiplexed Luciferase-based Screening Platform for Interrogating Cancer-associated Signal Transduction in Cultured Cells
Published on: July 3, 2013
[Responsible cancer screening]
André L M Verbeek1, Jos A A M van Dijck, Labertus A L M Kiemeney
1Universitair Medisch Centrum St Radboud, afd. Epidemiologie, Biostatistiek en HTA, Nijmegen, the Netherlands. A.Verbeek@ebh.umcn.nl
Nederlands Tijdschrift Voor Geneeskunde
|November 17, 2011
Summary
Cancer screening programs in the Netherlands reduce mortality but lead to unnecessary referrals. Breast, cervical, colorectal, prostate, and lung cancer screenings show benefits alongside drawbacks like increased hospital visits.
Area of Science:
- Oncology
- Public Health
- Medical Diagnostics
Context:
- The Netherlands has established national screening programs for breast and cervical cancer.
- Colorectal cancer screening is under development, with ongoing research into prostate and lung cancer screening effectiveness.
- Screening investigations aim to reduce cancer-related mortality.
Purpose:
- To evaluate the benefits and drawbacks of national cancer screening programs in the Netherlands.
- To quantify the impact of screening on cancer mortality and healthcare resource utilization.
Summary:
- National screening programs for breast, cervical, colorectal, prostate, and lung cancer are implemented or under investigation in the Netherlands.
- These programs effectively reduce cancer-related deaths but also result in a significant number of unnecessary referrals to hospitals for further diagnosis.
- Hospitals anticipate substantial referral volumes, particularly for colorectal cancer screening, while general practices manage positive screening results for breast and cervical cancers.
Impact:
- Screening contributes to reduced cancer mortality rates across multiple cancer types.
- Increased hospital referrals due to screening place a burden on healthcare resources.
- Accurate risk-benefit assessments are crucial for optimizing cancer screening strategies and patient management.
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