Related Experiment Video
Updated: May 27, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
Neuroimaging of migrational disorders in pediatric epilepsy
M Reza Taheri1, Andres Krauthamer, Jeff Otjen
1Department of Radiology, The George Washington University Hospital, Washington, DC, USA. rtaheri@mfa.gwu.edu
Insights
Pediatric seizures, often caused by brain insults, may require neuroimaging for diagnosis. Advanced techniques like MRI and PET scans help pinpoint seizure origins, improving treatment and outcomes.
Area of Science:
- Pediatric neurology
- Neuroradiology
- Neuroscience
Background:
- Seizures in children are a frequent neurological symptom with diverse underlying causes.
- While not always necessary, neuroimaging is crucial for diagnosing specific pediatric seizure cases.
- Identifying the seizure focus is essential for effective patient management.
Purpose of the Study:
- To review the role and methods of neuroimaging in the evaluation of pediatric seizures.
- To highlight the importance of advanced imaging techniques in diagnosing seizure etiologies.
- To emphasize the impact of early and accurate diagnosis on patient prognosis.
Main Methods:
- Review of clinical indications for neuroimaging in pediatric epilepsy.
- Discussion of magnetic resonance imaging (MRI) as the primary modality.
- Exploration of complementary roles for positron emission tomography (PET) and diffusion tensor imaging (DTI).
Main Results:
- Neuroimaging is reserved for a subset of pediatric patients based on clinical and EEG findings.
- Disorders of cortical development are significant causes of pediatric seizures.
- Advanced imaging modalities offer complementary diagnostic information.
Conclusions:
- Neuroimaging is a vital tool in the workup of specific pediatric seizure cases.
- Advanced imaging techniques enhance the identification of seizure foci and underlying pathologies.
- Timely and precise diagnosis through imaging improves treatment strategies and patient outcomes.
Abstract:
Seizures in children are common and represent a final pathway for a variety of brain insults. Although most children with seizures do not require imaging, when indicated, imaging plays an important role in the clinical workup. Imaging in the pediatric seizure population is reserved for a particular subset of patients depending on factors, such as age of onset, symptomatology, physical examination findings, and specific electroencephalography changes to name a few. The etiologies of seizures are extensive and include disorders of cortical migration and organization. Cortical migration and organization disorders are multifactorial and complex and a major cause of seizure disorders. Although magnetic resonance imaging is the most common imaging modality used to identify the seizure focus, positron emission tomographic and/or diffusion tensor imaging are beginning to provide complementary information about the involved areas. Early and accurate detection is key to better treatment and overall improved patient prognosis.
More Related Videos
10:22Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
Published on: December 6, 2016
08:23A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
Published on: November 13, 2016