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Related Experiment Video

Updated: May 27, 2026

Microfluidic-based Synthesis of Covalent Organic Frameworks (COFs): A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface
08:42

Microfluidic-based Synthesis of Covalent Organic Frameworks (COFs): A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface

Published on: July 10, 2017

Pore surface engineering in covalent organic frameworks.

Atsushi Nagai1, Zhaoqi Guo, Xiao Feng

  • 1Department of Materials Molecular Science, Institute for Molecular Science, National Institutes of Natural Sciences, Okazaki, Japan.

Nature Communications
|November 17, 2011
PubMed
Summary
This summary is machine-generated.

Pore surface engineering in covalent organic frameworks (COFs) is now possible. This method uses azide-appended building blocks and click chemistry for controlled functionalization of COF pore walls.

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Last Updated: May 27, 2026

Microfluidic-based Synthesis of Covalent Organic Frameworks (COFs): A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface
08:42

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Determining Surface Areas and Pore Volumes of Metal-Organic Frameworks

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Synthesis and Characterization of Functionalized Metal-organic Frameworks
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Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

Area of Science:

  • Materials Science
  • Organic Chemistry
  • Nanotechnology

Background:

  • Covalent organic frameworks (COFs) are porous materials with tunable pore size and geometry.
  • Precise control over COF pore surface chemistry is crucial but remains a significant challenge.

Purpose of the Study:

  • To introduce a novel method for pore surface engineering in COFs.
  • To enable controlled functionalization of COF pore walls with specific organic groups.

Main Methods:

  • Synthesis of COFs using azide-appended building blocks.
  • Utilizing click chemistry (azide-alkyne cycloaddition) for quantitative pore wall functionalization.
  • Demonstrating the versatility of the method with various alkyne click partners.

Main Results:

  • Achieved controlled and designable functionalization of COF pore surfaces.
  • Demonstrated the quantitative nature of the click reaction for appending organic groups.
  • Showcased the compatibility of the protocol with diverse click reactions, leading to various specific pore surfaces.

Conclusions:

  • This methodology represents a significant advancement in pore surface engineering for COFs.
  • Enables the realization of pre-designed compositions, components, and functions within COFs.
  • Opens new avenues for tailoring COF properties for specific applications.