Related Experiment Video
Updated: May 27, 2026

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms
Published on: April 17, 2026
Autoimmune pancreatitis exhibiting multiple mass lesions
Masahiro Shiokawa1, Yuzo Kodama, Yukiko Hiramatsu
1Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
This case report details autoimmune pancreatitis presenting as multiple pancreatic masses, diagnosed via EUS-FNA and treated successfully with steroids. The findings highlight a rare presentation of autoimmune pancreatitis and guide diagnosis to avoid unnecessary surgery.
Area of Science:
- Gastroenterology
- Pathology
- Endocrinology
Background:
- Autoimmune pancreatitis (AIP) is a chronic inflammatory condition of the pancreas.
- AIP can present with diverse imaging findings, sometimes mimicking pancreatic cancer.
- Accurate diagnosis is crucial to guide appropriate treatment and prognosis.
Observation:
- A unique case of AIP presenting with multiple pancreatic masses is described.
- Diagnosis was confirmed through endoscopic ultrasound-guided fine needle aspiration (EUS-FNA).
- The pancreatic masses showed complete resolution following steroid therapy.
Findings:
- This is the first reported case of AIP exhibiting multiple pancreatic masses.
- EUS-FNA proved effective for pathological diagnosis of AIP in this presentation.
- Steroid treatment led to the complete disappearance of the pancreatic masses.
Implications:
- Autoimmune pancreatitis should be considered in the differential diagnosis of multiple pancreatic masses.
- This case underscores the importance of minimally invasive diagnostic techniques like EUS-FNA.
- Appropriate diagnosis of AIP can prevent unnecessary surgical interventions for pancreatic masses.
Related Concept Videos
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Pathophysiology
Acute Pancreatitis II: Pathophysiology
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Acute Pancreatitis II: Clinical Manifestations and Management

