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The role of progesterone in traumatic brain injury

Tamara R Espinoza1, David W Wright

  • 1Department of Emergency Medicine and Division of Emergency Neurosciences, Emory University School of Medicine, Atlanta, Georgia 30303, USA. tamara.espinoza@emory.edu

The Journal of Head Trauma Rehabilitation
|November 18, 2011
PubMed
Abstract

No abstract available in PubMed .

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Traumatic Brain Injury l: Introduction01:28

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DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
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Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...

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