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Toxic psychosis due to chloroquine--not uncommon in children

P Garg1, P Mody, K B Lall

  • 1Department of Pediatrics & Neonatology, J.L.N. Medical College, Ajmer, India.

Clinical Pediatrics
|August 1, 1990
PubMed

Insights

Pediatric toxic psychosis from Chloroquine is rare but important for doctors to consider in unexplained childhood psychosis cases. Early diagnosis can prevent extensive, unnecessary investigations.

Area of Science:

  • Pediatric toxicology
  • Neuropsychiatry

Background:

  • Chloroquine is an antimalarial and anti-inflammatory drug.
  • Toxic psychosis is a rare adverse effect, especially in children.

Observation:

  • Four pediatric cases of psychosis linked to Chloroquine were observed over 18 months.
  • Symptoms varied widely among the affected children.

Findings:

  • Chloroquine toxicity can manifest as psychosis in children.
  • This diagnosis should be considered in unexplained pediatric psychosis.

Implications:

  • Familiarizing pediatricians with Chloroquine-induced toxic psychosis is crucial.
  • Considering this diagnosis early can streamline patient management and avoid unnecessary tests.

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