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Updated: May 27, 2026

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
Published on: September 17, 2014
Persistent lamellar interface fluid with clear cornea after Descemet stripping automated endothelial keratoplasty
Volkan Hurmeric1, Jianhua Wang, George D Kymionis
1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Purpose:
To describe clinical properties of a patient with persistent interface fluid syndrome and clear graft, 3.5 years after Descemet stripping automated endothelial keratoplasty (DSAEK).
Methods:
Case report.
Results:
A 69-year-old woman who had DSAEK in 2006 presented with a clear cornea (no corneal edema) and deep diffuse reticular haze in the right eye. Visual acuity was 20/40. Ultrahigh-resolution optical coherence tomography (UHR-OCT) imaging of the right eye demonstrated persistent interface fluid at the donor-recipient junction. The detachment between donor and recipient corneas was 70 μm at the center. There was no connection between the anterior chamber and the donor/recipient interface.
Conclusions:
Despite the persistent detachment of the donor cornea, the recipient cornea can remain clear in persistent interface fluid syndrome after DSAEK.

