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Related Concept Videos

Active versus Passive Immunity01:31

Active versus Passive Immunity

Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
Immunological Memory01:23

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
Vaccinations01:51

Vaccinations

Overview

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Related Experiment Video

Updated: May 27, 2026

Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay
06:15

Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay

Published on: September 7, 2018

General session 3: acquired immunity.

JoAnn C L Schuh1, Gail Pearse

  • 1JCL Schuh, PLLC, Bainbridge Island, Washington 98110-3663, USA. schuhj@jclschuh.com

Toxicologic Pathology
|November 18, 2011
PubMed
Summary

This session explored advances in acquired immunity, focusing on T and B lymphocytes. It covered how regulatory T cells and immune dysregulation contribute to diseases like immunosuppression and autoimmunity.

Area of Science:

  • Toxicologic Pathology
  • Immunology
  • Cellular Biology

Background:

  • Acquired immunity provides specific recognition and memory against antigens, involving T and B lymphocytes.
  • It complements innate immunity for robust host defense.
  • Dysfunction in acquired immunity can lead to various pathological conditions.

Purpose of the Study:

  • To review biological advances in the control of acquired immunity.
  • To highlight the role of regulatory T cells in immune function and dysfunction.
  • To discuss the pathophysiology of immune-mediated diseases.

Main Methods:

  • Review of recent advancements in understanding acquired immunity.
  • Analysis of regulatory T cell function.
  • Examination of effector cell and secretory molecule roles in disease.

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Measuring Naturally Acquired Phagocytosis-Inducing Antibodies to Plasmodium falciparum Parasites by a Flow Cytometry-Based Assay

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Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
09:57

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens

Published on: February 14, 2011

Related Experiment Videos

Last Updated: May 27, 2026

Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay
06:15

Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay

Published on: September 7, 2018

Measuring Naturally Acquired Phagocytosis-Inducing Antibodies to Plasmodium falciparum Parasites by a Flow Cytometry-Based Assay
09:57

Measuring Naturally Acquired Phagocytosis-Inducing Antibodies to Plasmodium falciparum Parasites by a Flow Cytometry-Based Assay

Published on: August 6, 2020

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
09:57

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens

Published on: February 14, 2011

Main Results:

  • Advances in understanding regulatory T cells and their impact on immune homeostasis.
  • Insights into the mechanisms of immunosuppression, allergic inflammation, and autoimmune diseases.
  • Identification of dysregulation leading to loss of self-tolerance.

Conclusions:

  • Acquired immunity is crucial for host defense, with complex regulatory mechanisms.
  • Dysregulation of acquired immunity underlies significant pathological conditions.
  • Further research into immune control is vital for therapeutic development.