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Related Concept Videos

Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Assessment of the Cardiovascular System II: Inspection01:29

Assessment of the Cardiovascular System II: Inspection

Inspection is the initial step in assessing the cardiovascular system. It involves a detailed visual examination that provides crucial information about a patient's circulatory and cardiac health. This systematic process, conducted from head to toe, helps identify signs of cardiovascular conditions by observing physical appearance, skin and mucous membranes, jugular and carotid pulsations, chest symmetry, and the condition of the extremities.
Head and Neck

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Related Experiment Video

Updated: May 27, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Evaluating hand in systemic sclerosis.

Didem Arslan Tas1, Eren Erken, Hakan Sakalli

  • 1Faculty of Medicine, Cukurova University, Adana, Turkey. arslan_didem@yahoo.com

Rheumatology International
|November 18, 2011
PubMed
Summary

Hand arthropathy in Systemic Sclerosis (SSc) is challenging. Radiography with rheumatoid factor (RF) and anti-CCP tests helps distinguish SSc arthropathy from rheumatoid arthritis (RA) overlap, guiding patient care.

Area of Science:

  • Rheumatology
  • Immunology
  • Radiology

Background:

  • Articular symptoms, particularly hand involvement, are frequent in Systemic Sclerosis (SSc).
  • Distinguishing SSc-related hand arthropathy from rheumatoid arthritis (RA) overlap is clinically challenging.
  • Understanding the nature of hand arthropathy in SSc is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To identify key features differentiating SSc-associated hand arthropathy from RA-SSc overlap.
  • To assess the utility of serological tests and radiographic findings in this differentiation.

Main Methods:

  • Retrospective analysis of 28 SSc patients and 43 controls (21 RA, 22 healthy).
  • Assessment of serological markers (anti-CCP antibody, RF), hand radiography, finger-to-palm distance, and clinical features.

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  • Evaluation of disease activity and functional scores.
  • Main Results:

    • SSc patients showed distinct radiographic findings including erosions, joint space narrowing, demineralization, acro-osteolysis, and contractures.
    • Rheumatoid factor (RF) and anti-CCP positivity were significantly lower in SSc compared to RA.
    • Two SSc patients (7.14%) met criteria for RA overlap (positive RF/anti-CCP, arthritis on radiographs).
    • Seventeen SSc patients (61%) had SSc arthropathy (negative RF/anti-CCP, non-arthritic radiographic findings).
    • Arthritis correlated with heart involvement; finger-to-palm distance correlated with lung involvement in SSc.

    Conclusions:

    • Hand radiography combined with RF and anti-CCP testing is valuable for discriminating SSc arthropathy from RA-SSc overlap.
    • Identifying hand arthropathy in SSc warrants increased attention to potential internal organ involvement.
    • This approach aids in precise diagnosis and management strategies for SSc patients with hand complaints.