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Expiratory flow increase technique and acid esophageal exposure in infants born preterm with bronchopulmonary
Lia Franco Serrou Camy1, Maria Aparecida Mezzacappa
1Center of Integral Attention to Women's Health, University of Campinas-UNICAMP, Campinas, São Paulo, Brazil. liacamy@gmail.com
Insights
Expiratory flow increase technique (EFIT) does not worsen acid reflux in preterm infants with bronchopulmonary dysplasia (BPD). Studies show EFIT, when used 2-3 hours post-feeding, is safe for managing BPD in these vulnerable infants.
Area of Science:
- Pediatrics
- Neonatology
- Respiratory Medicine
Background:
- Bronchopulmonary dysplasia (BPD) is a chronic lung disease common in preterm infants.
- Acid reflux is a frequent complication in infants with BPD, potentially impacting respiratory outcomes.
- The expiratory flow increase technique (EFIT) is used to aid airway clearance in infants with BPD.
Purpose of the Study:
- To investigate the association between the expiratory flow increase technique (EFIT) and gastroesophageal acid reflux episodes.
- To assess the safety of EFIT in preterm infants diagnosed with bronchopulmonary dysplasia (BPD).
Main Methods:
- A randomized crossover study involving 18 preterm infants with BPD.
- Infants were assigned to two groups, receiving EFIT sessions at 2 or 3 hours postprandial.
- Esophageal pH monitoring assessed the reflux index (RI) before and during EFIT.
Main Results:
- A significant reduction in the reflux index (RI) was observed when EFIT was performed 2 hours after feeding (Group 1).
- No significant difference in RI was found before and during EFIT in infants tested 3 hours after feeding (Group 2).
- EFIT was not associated with an increase in acid reflux episodes in either group.
Conclusions:
- The expiratory flow increase technique (EFIT) is not associated with an increase in acid reflux episodes.
- Performing EFIT 2 to 3 hours after feeding appears safe for preterm infants with BPD regarding acid reflux.
Objective:
To determine if an expiratory flow increase technique (EFIT) is associated with acid reflux episodes in infants born preterm with bronchopulmonary dysplasia (BPD).
Methods:
A crossover study was carried out. Eighteen subjects divided into 2 groups were randomly assigned to receive 2 EFIT sessions at 2 postprandial time points. Group 1 started 2 hours after feeding and group 2 started 3 hours after feeding. Esophageal acid exposure was assessed by the reflux index (RI) during EFIT and 20 minutes before EFIT by esophageal pH monitoring.
Results:
A significant reduction in the RI was observed in group 1 with EFIT performed 2 hours after feeding. Group 2 showed no significant differences in RI values before and during EFIT in both postprandial periods.
Conclusion:
When EFIT is performed 2 and 3 hours after feeding, it is not associated with an increase in acid reflux episodes in infants born preterm with BPD.
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