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Expiratory flow increase technique and acid esophageal exposure in infants born preterm with bronchopulmonary

Lia Franco Serrou Camy1, Maria Aparecida Mezzacappa

  • 1Center of Integral Attention to Women's Health, University of Campinas-UNICAMP, Campinas, São Paulo, Brazil. liacamy@gmail.com

Insights

Expiratory flow increase technique (EFIT) does not worsen acid reflux in preterm infants with bronchopulmonary dysplasia (BPD). Studies show EFIT, when used 2-3 hours post-feeding, is safe for managing BPD in these vulnerable infants.

Area of Science:

  • Pediatrics
  • Neonatology
  • Respiratory Medicine

Background:

  • Bronchopulmonary dysplasia (BPD) is a chronic lung disease common in preterm infants.
  • Acid reflux is a frequent complication in infants with BPD, potentially impacting respiratory outcomes.
  • The expiratory flow increase technique (EFIT) is used to aid airway clearance in infants with BPD.

Purpose of the Study:

  • To investigate the association between the expiratory flow increase technique (EFIT) and gastroesophageal acid reflux episodes.
  • To assess the safety of EFIT in preterm infants diagnosed with bronchopulmonary dysplasia (BPD).

Main Methods:

  • A randomized crossover study involving 18 preterm infants with BPD.
  • Infants were assigned to two groups, receiving EFIT sessions at 2 or 3 hours postprandial.
  • Esophageal pH monitoring assessed the reflux index (RI) before and during EFIT.

Main Results:

  • A significant reduction in the reflux index (RI) was observed when EFIT was performed 2 hours after feeding (Group 1).
  • No significant difference in RI was found before and during EFIT in infants tested 3 hours after feeding (Group 2).
  • EFIT was not associated with an increase in acid reflux episodes in either group.

Conclusions:

  • The expiratory flow increase technique (EFIT) is not associated with an increase in acid reflux episodes.
  • Performing EFIT 2 to 3 hours after feeding appears safe for preterm infants with BPD regarding acid reflux.
Abstract

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