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Direct comparison of the traditional and reverse syphilis screening algorithms in a population with a low prevalence

Matthew J Binnicker1, Deborah J Jespersen, Leonard O Rollins

  • 1Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, College of Medicine, Mayo Clinic, Rochester, Minnesota, USA. binnicker.matthew@mayo.edu

Journal of Clinical Microbiology
|November 18, 2011
PubMed

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Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...