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Related Concept Videos

Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Psychosexual Stages of Personality: Oral01:16

Psychosexual Stages of Personality: Oral

The oral stage is the initial phase of Sigmund Freud's theory of psychosexual development, occurring from birth to approximately 12 to 18 months. During this period, the infant's mouth serves as the primary source of pleasure, with actions such as sucking, chewing, biting, and drinking playing a crucial role in reducing tension. These activities are essential not only for nourishment but also for the infant's psychological and emotional satisfaction.
Weaning, typically occurring around the age...
Tooth Anatomy01:21

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

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Related Experiment Video

Updated: May 27, 2026

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

Pierre robin sequence and the pediatric dentist.

B N Rangeeth1, Joyson Moses, N Venugopal Reddy

  • 1Thai Moogambigai Dental College and Hospital, Mogappair, Chennai, India.

Contemporary Clinical Dentistry
|November 18, 2011
PubMed
Summary

This case report details the dental management of a neonate with Pierre Robin sequence and cleft palate. A feeding plate was constructed to address feeding difficulties, a common complication of this condition.

Keywords:
Cleft palatePierre Robin syndromefeeding obturatorfeeding platesyndromic cleft

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Last Updated: May 27, 2026

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

Area of Science:

  • Pediatric Dentistry
  • Craniofacial Anomalies
  • Neonatal Care

Background:

  • Pierre Robin sequence is a congenital condition characterized by micrognathia, glossoptosis, and airway obstruction.
  • Cleft palate is frequently associated with Pierre Robin sequence, complicating feeding and speech.
  • Neonatal feeding difficulties require prompt and effective management to ensure proper growth and development.

Observation:

  • A 56-day-old neonate presented with significant feeding difficulties.
  • The neonate was diagnosed with Pierre Robin sequence and a cleft palate.
  • Clinical and laboratory procedures were initiated for dental management.

Findings:

  • Construction of a custom feeding plate was performed to facilitate oral feeding.
  • The feeding plate addressed the anatomical challenges posed by the cleft palate and micrognathia.
  • Literature review highlighted potential medical complications associated with Pierre Robin sequence.

Implications:

  • Early dental intervention, including feeding plate fabrication, is crucial for neonates with Pierre Robin sequence.
  • Effective management of feeding difficulties can prevent failure to thrive and reduce medical complications.
  • This case highlights the importance of a multidisciplinary approach in managing complex congenital conditions.