Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Phosphoinositides and PIPs

Phosphoinositides and PIPs

Phosphoinositides are a group of phospholipids containing a glycerol backbone with two fatty acid chains and a phosphate attached to a myoinositol sugar ring. The inositol head group extends into the cytoplasm, where it is modified by adding phosphate groups to form phosphatidylinositol phosphates or PIPs.
Different phosphoinositides are synthesized and recruited on the cytosolic face of the plasma membrane. The localization of specific phosphoinositides concentrated in separate membrane...

Phosphorylation

Phosphorylation

The addition or removal of phosphate groups from proteins is the most common chemical modification that regulates cellular processes. These modifications can affect the structure, activity, stability, and localization of proteins within cells as well as their interactions with other proteins.
During phosphorylation, protein kinases transfer the terminal phosphate group of ATP to specific amino acid side chains of substrate proteins. Serine, threonine, and tyrosine are the most commonly...

Phosphorylation

Phosphorylation

The addition or removal of phosphate groups from proteins is the most common chemical modification that regulates cellular processes. These modifications can affect the structure, activity, stability, and localization of proteins within cells as well as their interactions with other proteins.
During phosphorylation, protein kinases transfer the terminal phosphate group of ATP to specific amino acid side chains of substrate proteins. Serine, threonine, and tyrosine are the most commonly...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Synthesis and herbicidal activity of optically active α-(substituted phenoxyacetoxy) (substituted phenyl) methylphosphonates.

Pesticide biochemistry and physiology·2017

Same author

Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins.

The Journal of biological chemistry·2017

Same author

S149R, a novel mutation in the <i>ABCD1</i> gene causing X-linked adrenoleukodystrophy.

Oncotarget·2017

Same author

Transgenic cotton co-expressing chimeric Vip3AcAa and Cry1Ac confers effective protection against Cry1Ac-resistant cotton bollworm.

Transgenic research·2017

Same author

Effective adsorption of nitroaromatics at the low concentration by a newly synthesized hypercrosslinked resin.

Water science and technology : a journal of the International Association on Water Pollution Research·2017

Same author

Comparative Genome Analysis Reveals Adaptation to the Ectophytic Lifestyle of Sooty Blotch and Flyspeck Fungi.

Genome biology and evolution·2017

Same journal

Crystal structure of 1-(piperidin-1-yl)butane-1,3-dione.

Acta crystallographica. Section E, Structure reports online·2015

Same journal

Crystal structure of methyl 1-methyl-3,5-diphenyl-7-tosyl-3,6,7,11b-tetra-hydro-pyrazolo-[4',3':5,6]pyrano[3,4-c]quinoline-5a(5H)-carboxyl-ate.

Acta crystallographica. Section E, Structure reports online·2015

Same journal

Crystal structure of 4-amino-1-(4-methyl-benz-yl)pyridinium bromide.

Acta crystallographica. Section E, Structure reports online·2015

Same journal

Crystal structure of (Z)-3-benz-yloxy-6-[(2-hy-droxy-anilino)methyl-idene]cyclo-hexa-2,4-dien-1-one.

Acta crystallographica. Section E, Structure reports online·2015

Same journal

Crystal structure of bis-(1-benzyl-1H-1,2,4-triazole) perchloric acid monosolvate.

Acta crystallographica. Section E, Structure reports online·2015

Same journal

Crystal structure of 2-(di-phenyl-phos-phanyl)phenyl 4-(hy-droxy-meth-yl)benzoate.

Acta crystallographica. Section E, Structure reports online·2015

See all related articles

Search research articles

Related Experiment Video

Updated: May 27, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

Published on: January 24, 2016

Ferrocenyl-phospho-nic acid.

Bao-Zhang Yang, Chao Xu, Tai-Ke Duan

Acta Crystallographica. Section E, Structure Reports Online

|November 18, 2011

Summary

This summary is machine-generated.

This study details a novel ferrocene derivative with a phosphate group linked by a P-C bond. Six molecules self-assemble via hydrogen bonds into a distorted octahedral cage, showcasing unique crystal packing in organometallic compounds.

More Related Videos

Quantitative Phosphoproteomics in Fatty Acid Stimulated Saccharomyces cerevisiae

Quantitative Phosphoproteomics in Fatty Acid Stimulated Saccharomyces cerevisiae

Published on: October 12, 2009

Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer

Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer

Published on: August 20, 2012

Related Experiment Videos

Last Updated: May 27, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

Published on: January 24, 2016

Quantitative Phosphoproteomics in Fatty Acid Stimulated Saccharomyces cerevisiae

Quantitative Phosphoproteomics in Fatty Acid Stimulated Saccharomyces cerevisiae

Published on: October 12, 2009

Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer

Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer

Published on: August 20, 2012

Area of Science:

Organometallic Chemistry
Crystal Engineering
Supramolecular Chemistry

Background:

Ferrocene derivatives are versatile building blocks in coordination chemistry and materials science.
Understanding intermolecular interactions is crucial for designing crystalline architectures.
Phosphorus-containing ferrocenes offer unique electronic and structural properties.

Purpose of the Study:

To synthesize and characterize a novel ferrocenyl-phospho-nic acid compound.
To investigate the crystal structure and intermolecular interactions of the title compound.
To explore the self-assembly behavior of ferrocene derivatives in the solid state.

Main Methods:

Single-crystal X-ray diffraction analysis to determine molecular and crystal structure.
Spectroscopic methods for compound characterization (e.g., NMR, IR).
Analysis of hydrogen bonding networks and cage formation.

Main Results:

The compound [Fe(C(5)H(5))(C(5)H(6)O(3)P)] features a direct P-C bond (1.749(3) Å) between the phosphate and ferrocene units.
Six molecules form a highly distorted octahedral cage through 12 strong intermolecular O-H⋯O hydrogen bonds.
The determined cage volume is approximately 270 Å³.

Conclusions:

The study reveals a novel organometallic compound with a unique P-C linkage to ferrocene.
Intermolecular hydrogen bonding drives the self-assembly into a discrete, albeit distorted, cage structure.
This work contributes to the understanding of crystal engineering principles in ferrocene-based systems.