Related Experiment Video
Updated: May 27, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
3,8-Dimethyl-quinazoline-2,4(1H,3H)-dione
Wei-Yan Qin1, Bo Liu, Cong-Wen Duan
1Key Laboratory of Green Chemical Technology, College of Heilongjiang Province, School of Chemistry and Environmental Engineering, Harbin University of Science and Technology, Harbin 150040, People's Republic of China.
Abstract:
In the title compound, C(10)H(10)N(2)O(2), all non-H atoms are approximately co-planar with an r.m.s. deviation of 0.016 Å. In the crystal, mol-ecules are linked into inversion dimers by pairs of N-H⋯O hydrogen bonds. Chains along [010] are buiilt up by π-π inter-actions [centroid-centroid distance = 3.602 (1) Å] between the benzene and piperazine rings of adjacent mol-ecules.
Related Concept Videos
Oxidation of Phenols to Quinones
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox property is crucial in...
Radical Chain-Growth Polymerization: Overview
Aryldiazonium Salts to Azo Dyes: Diazo Coupling
Structure and Nomenclature of Alcohols and Phenols
Alcohols are one of the most important functional groups in organic chemistry. The name of alcohol comes from the hydrocarbon from which it is derived. Alcohols are organic molecules containing the functional hydroxyl or –OH group directly bonded to carbon. Phenols have an OH group directly attached to a benzene ring. While alcohols are colorless, phenol is a white crystalline compound with a characteristic "hospital smell" odor.
As with other organic compounds, alcohols and phenols...
Diazonium Group Substitution: –OH and –H

