Related Experiment Video
Updated: May 27, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
(E)-N'-[4-(Dimethyl-amino)-benzyl-idene]-4-methyl-benzohydrazide methanol monosolvate
Huanyu Liu1, Yanchun Cai, Jianyong Wu
1School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan 528453, People's Republic of China.
Abstract:
In the title compound, C(17)H(19)N(3)O·CH(3)OH, the hydrazone mol-ecule exists in a trans geometry with respect to the methyl-idene unit and the dihedral angle between the two substituted benzene rings is 42.6 (2)°. In the crystal, the components are linked through N-H⋯O and O-H⋯O hydrogen bonds, forming [100] chains of alternating hydrazone and methanol mol-ecules.
Related Concept Videos
Diazonium Group Substitution: –OH and –H
Dehydration of Aldols to Enals: Base-Catalyzed Aldol Condensation
Carboxylic Acids to Methylesters: Alkylation using Diazomethane
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration
Alkylation of β-Diester Enolates: Malonic Ester Synthesis
Dehydration of Aldols to Enones: Acid-Catalyzed Aldol Condensation

