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Updated: May 27, 2026

One-pot Microwave-assisted Conversion of Anomeric Nitrate-esters to Trichloroacetimidates
Published on: January 15, 2018
5-Chloro-6-hy-droxy-7,8-dimethyl-chroman-2-one
Scott A Cameron1, Shailesh K Goswami, Lyall R Hanton
1Department of Chemistry, University of Otago, PO Box 56, Dunedin, New Zealand.
Abstract:
In the title mol-ecule, C(11)H(11)ClO(3), the fused pyran ring adopts a half-chair conformation. In the crystal, inter-molecular O-H⋯O hydrogen bonds link mol-ecules into chains along [100]. These chains are inter-connected by weak inter-molecular C-H⋯O contacts which generate R(2) (2)(8) ring motifs, forming sheets parallel to (001). Tetra-gonal symmetry generates an equivalent motif along b. Furthermore, the sheets are linked along the c axis by offset π-π stacking inter-actions involving the benzene rings of adjacent mol-ecules [with centroid-centroid distances of 3.839 (2) Å], together with an additional weak C-H⋯O hydrogen bond, resulting in an overall three-dimensional network.
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