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A systematic review of randomized controlled interventions for parents' distress in pediatric leukemia
A Bougea1, C Darviri, E C Alexopoulos
1Stress Management and Health Promotion Postgraduate Course, Medical School, University of Athens, 115 27 Athens, Greece.
Insights
This review found that combined cognitive-behavioral interventions effectively reduce stress in parents of children with leukemia. Further research is needed to explore other psychological interventions and improve trial design quality.
Area of Science:
- Pediatric Oncology
- Psychological Interventions
- Family Wellbeing
Background:
- Parental stress is a significant concern for families with a child diagnosed with leukemia.
- Effective interventions are crucial for improving child and family wellbeing.
Purpose of the Study:
- To systematically review evidence on interventions reducing parental stress in childhood leukemia.
- To assess the impact of these interventions on child and family wellbeing.
Main Methods:
- Systematic review of randomized controlled trials (RCTs) from January 1980 to June 2010 using MEDLINE.
- Inclusion of 7 RCTs with 1045 parent participants.
- Assessment of outcomes via self-report, observer report, and physiological measures.
Main Results:
- Combined cognitive-behavioral interventions demonstrated the most significant effect in reducing parental distress.
- Various psychological interventions, including problem-solving skills training, were utilized.
- Methodological limitations included heterogeneity in stress measurement and inadequate adjustment for moderating factors.
Conclusions:
- Combined cognitive-behavioral interventions are recommended for managing parental stress in childhood leukemia.
- Further RCTs should prioritize robust trial design and reporting quality.
- Limited evidence suggests potential benefits from other psychological interventions.
Abstract:
Objective. This review aims to summarize the existing evidence concerning interventions towards reducing stress in parents with a child with leukemia and their effect in child and family wellbeing. Methods. A systematic review strategy was conducted using MEDLINE covering the period January 1980 to June 2010. Results. Seven randomized controlled trials met the inclusion criteria including in total 1045 parents participants. A variety of cognitive-behavioral interventions problem-solving skills training programs have been used for managing distress in parents and children. Outcome measures are assessed by self-report, observer report, behavioral/psychological, and physiological measures. The most prominent methodological problems were the marked heterogeneity in stress measurement and the relative absence of proper measurement and adjustment of moderating and mediating factors. The largest effect has been obtained by combined cognitive-behavioral interventions with promising but limited evidence for several other psychological interventions. Conclusions. Recommendations for future RCTs are provided, and particular attention to the quality of trial design and reporting is highlighted.
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