[Preovulatory human oocyte and its hormonal microenvironment in stimulated cycles]

The hormonal microenvironment of 213 follicles in 44 stimulated cycles was analysed. Mature and intermediate oocytes were found to be associated with larger follicles which contained significantly higher levels of E2, P, FSH and LH, while smaller follicles containing significantly higher T level usually gave rise to immature oocytes. The fertilization rate was higher in mature and intermediate oocytes than in immature oocytes. In this study there was no significant difference in the cleavage rate of the fertilized eggs in relation to the E2, P, T, FSH and LH concentrations in follicular fluid as well as to the contents of these hormones per follicle.