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Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

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Related Experiment Video

Updated: May 27, 2026

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats

Published on: March 30, 2018

The benefits and risks of stem cell technology.

A Leventhal¹, G Chen, A Negro

¹Center for Molecular Medicine,National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10-CRC, Room 5-3132, Bethesda, MD 20817, USA.

|November 19, 2011

Summary

Stem cell technology offers vast potential for future medical and dental therapies and understanding disease mechanisms. Clinicians will need to understand stem cell biology and therapeutics for future practice.

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Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats

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Area of Science:

Regenerative Medicine
Stem Cell Biology
Clinical Therapeutics

Background:

Stem cell technology presents significant potential to revolutionize medical and dental practices.
Ongoing research provides foundational knowledge for novel therapeutic strategies.
Understanding stem cell biology is crucial for advancing disease mechanism insights.

Purpose of the Study:

To provide a foundational overview of stem cell biology.
To introduce stem cell therapeutics relevant to clinical practice.
To prepare clinicians for the integration of stem cell technology.

Main Methods:

Review of current stem cell biology principles.
Summary of established and emerging stem cell therapeutic applications.
Discussion of clinical relevance and future implications.

Main Results:

Stem cell research is key to developing future therapies.
Stem cells offer unique insights into fundamental disease mechanisms.
Knowledge of stem cell biology is becoming essential for clinicians.

Conclusions:

Stem cell technology holds vast potential for medicine and dentistry.
A grasp of stem cell biology and therapeutics is necessary for future clinical practice.
This overview equips clinicians with essential knowledge in stem cell technology.