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Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
Published on: April 18, 2025
Contrast stress echocardiography in hypertensive heart disease
Mai Tone Lønnebakken1, Ashild E Rieck, Eva Gerdts
1Department of Heart Disease, Haukeland University Hospital, Bergen, Norway. mai.tone.lonnebakken@helse-bergen.no
Insights
Hypertension can cause myocardial ischemia without coronary artery disease via left ventricular hypertrophy and arterial stiffness. Contrast stress echocardiography diagnosed this in a patient with resistant hypertension and angina.
Area of Science:
- Cardiology
- Hypertension Research
- Diagnostic Imaging
Background:
- Hypertension is linked to atherosclerosis and cardiovascular changes.
- Myocardial ischemia in hypertension can occur independently of coronary artery disease.
- Pathophysiological mechanisms include left ventricular hypertrophy, arterial stiffness, and endothelial dysfunction.
Observation:
- A case report details a hypertensive patient experiencing angina pectoris.
- The patient had no significant obstructive coronary artery disease.
- Diagnostic challenge: differentiating ischemia causes in hypertensive patients.
Findings:
- Contrast stress echocardiography identified myocardial ischemia.
- Ischemia was attributed to severe resistant hypertension.
- Complications included concentric left ventricular hypertrophy and increased arterial stiffness.
Implications:
- Highlights the utility of contrast stress echocardiography in diagnosing non-obstructive ischemic heart disease in hypertensive patients.
- Emphasizes the cardiac impact of resistant hypertension, including structural and functional changes.
- Suggests a need for comprehensive cardiovascular assessment in hypertensive individuals presenting with angina.
Abstract:
Hypertension is associated with atherosclerosis and cardiac and vascular structural and functional changes. Myocardial ischemia may arise in hypertension independent of coronary artery disease through an interaction between several pathophysiological mechanisms, including left ventricular hypertrophy, increased arterial stiffness and reduced coronary flow reserve associated with microvascular disease and endothelial dysfunction. The present case report demonstrates how contrast stress echocardiography can be used to diagnose myocardial ischemia in a hypertensive patient with angina pectoris but without significant obstructive coronary artery disease. The myocardial ischemia was due to severe resistant hypertension complicated with concentric left ventricular hypertrophy and increased arterial stiffness.
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