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Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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Dirlotapide as a model substrate to refine structure-based drug design strategies on CYP3A4-catalyzed metabolism

Hao Sun1, Andrew J Bessire, Alfin Vaz

  • 1Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc., Groton, CT 06340, United States. hao.sun@pfizer.com

Bioorganic & Medicinal Chemistry Letters
|November 19, 2011
PubMed

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