Related Experiment Video
Updated: Aug 17, 2026

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
[Left ventricle diastolic function in hypertensive patients and responses to captopril]
1Anhui Provincial Hospital, Hefei.
Abstract:
The LV diastolic function of 37 cases with primary hypertension were studied by measuring the diastolic filling blood stream at mitral orifice using pulsed Doppler echocardiography. 30/37 (81%) patients were found to have impaired LV diastolic function as compared with 30 normals of a group at similar age. After 4 weeks of oral captopril treatment in 20/37 patients, BP dropped in 19/20; LV diastolic function improved in 75-80%; left ventricular mass also regressed in 16/20 captopril treated patients (210 +/- 62 vs 171 +/- 46 g, P less than 0.01). It showed that captopril is not only effective in lowering blood pressure but also in improving the impaired LV diastolic function.
More Related Videos
08:21Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice
Published on: June 15, 2020
08:57Pulsed Wave Doppler Assessment of Diastolic Dysfunction in the ZSF-1 Rat Model of Pulmonary Hypertension Due to Left Heart Disease
Published on: May 22, 2026
Related Concept Videos
Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors
Pathophysiology of Heart Failure
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Mitral Regurgitation I: Introduction
Heart Failure II: Pathophysiology
Heart Failure V: Medical Management