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Updated: May 27, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
Published on: February 21, 2018
Collaboration between PcG proteins and MLL fusions in Leukemogenesis: an emerging paradigm
Bernd B Zeisig1, Mari-Francis Arteaga, Cecile Thirant
1Leukaemia and Stem Cell Biology Group, Department of Haematological Medicine, Rayne Institute, King's College London, SE5 9NU London, UK.
None:
PcG and TrxG proteins mostly with opposite transcriptional activities play key roles in normal and malignant development. In this issue of Cancer Cell, Tan et al. report an unexpected collaboration between CBX8 and MLL-AF9 in leukemia, revealing a far more complicated functional crosstalk between these master epigenetic regulators in oncogenesis.
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