Related Experiment Video
Updated: May 27, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Aortic-neck dilation after endovascular abdominal aortic aneurysm repair (EVAR): can it be predicted?
R Iezzi1, M Santoro, G Di Natale
1Department of Bioimaging and Radiological Sciences, Institute of Radiology, A. Gemelli Hospital, Catholic University, L.go A. Gemelli 8, 00168, Rome, Italy. roberto.iezzi@rm.unicatt.it
Purpose:
This study was performed to evaluate whether dynamic computed tomography (CT) can provide functional vessel information predicting outcomes of aortic neck in patients undergoing endovascular aneurysm repair (EVAR) of an abdominal aortic aneurysm (AAA).
Materials And Methods:
Twenty patients with and 20 without AAA were enrolled. Electrocardiographically (ECG)-gated data sets were acquired with a 64-slice CT scanner. Axial pulsatility measurements were taken at three levels: 2 cm above the highest renal artery; immediately below the lowest renal artery; 1 cm below the lowest renal artery. Three independent readers performed the measurements. Systolic and diastolic blood pressures were measured in the brachial artery to calculate arterial-wall distensibility expressed as pressure strain elastic modulus (Ep). Cross-sectional area change, wall distensibility and Ep value were statistically compared.
Results:
No significant differences were found in terms of Ep values in the suprarenal and juxtarenal level. In the AAA group, a significantly higher value was obtained at the infrarenal level. A subgroup of patients with AAA (45%) had a significantly higher Ep value at the infrarenal level.
Conclusions:
Dynamic CT provided insight into the abdominal aorta pathophysiology. Identifying patients with higher infrarenal distensibility could change selection of graft size to improve proximal fixation.
Related Concept Videos
Aneurysm III: Interprofessional Care
Aneurysm IV: Nursing Management
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aneurysm I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation III: Medical Management