Related Experiment Video
Updated: May 27, 2026
Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
High resolution three-dimensional cine phase contrast MRI of small intracranial aneurysms using a stack of stars
Steven Kecskemeti1, Kevin Johnson, Yijing Wu
1Department of Physics, University of Wisconsin, Madison, Wisconsin, USA. kecskemeti@wisc.edu
Purpose:
To develop a method for targeted volumetric, three directional cine phase contrast (PC) imaging with high spatial resolution in clinically feasible scan times.
Materials And Methods:
A hybrid radial-Cartesian k-space trajectory is used for cardiac gated, volumetric imaging with three directional velocity encoding. Imaging times are reduced by radial undersampling and temporal viewsharing. Phase contrast angiograms are displayed in a new approach that addresses the concern of signal drop out in regions of slow flow. The feasibility of the PC stack of stars (SOS) trajectory was demonstrated with an in vivo study capturing 14 small intracranial aneurysms (2-10 mm). Aneurysm measures from six aneurysms also imaged with digital subtraction angiography (DSA) were compared with linear regression with those from the PC SOS images.
Results:
All aneurysms were identified on the phase contrast angiograms. The geometric measures from PC SOS and DSA were in good agreement (linear regression: slope = 0.89, intercept = 0.35, R∧2 = 0.88).
Conclusion:
PC SOS is a promising method for obtaining volumetric angiograms and cine phase contrast velocity measurements in three dimensions. Acquired spatial resolutions of 0.4 × 0.4 × (0.7-1.0) mm make this method especially promising for studying flow in small intracranial aneurysms.
