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Related Experiment Video

Updated: May 27, 2026

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
13:37

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

Tumor lysis syndrome developing intraoperatively.

Ankur Verma1, Ruchi Mathur, Munish Chauhan

  • 1Department of Anaesthesiology, Dharmshila Cancer Hospital and Research Centre, Vasundhara Enclave, Shahdara, India.

Journal of Anaesthesiology, Clinical Pharmacology
|November 19, 2011
PubMed
Summary
This summary is machine-generated.

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See all related articles

Spontaneous tumor lysis syndrome can occur during surgery, even before chemotherapy. This rare perioperative complication, seen in undiagnosed Burkitt

Area of Science:

  • Oncology
  • Nephrology
  • Critical Care Medicine

Background:

  • Tumor lysis syndrome (TLS) is a critical oncologic emergency.
  • TLS is typically associated with chemotherapy initiation for high-grade malignancies.
  • Prompt recognition and management are vital to prevent severe morbidity and mortality.

Observation:

  • A case of spontaneous tumor lysis syndrome (TLS) occurring intraoperatively is presented.
  • The patient had undiagnosed Burkitt's lymphoma.
  • Clinical presentation included characteristic electrolyte abnormalities and milky urine post-laparotomy.

Findings:

  • Intraoperative tumor handling and laparotomy precipitated TLS in this undiagnosed lymphoma case.
  • This highlights a rare perioperative presentation of TLS.
Keywords:
Burkitt lymphomaContinuous venous-venous hemodialysisintraoperativelytumor lysis syndromeventricular arrhythmia

Related Experiment Videos

Last Updated: May 27, 2026

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
13:37

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

  • Electrolyte disturbances and urine appearance were key diagnostic indicators.

    • Implications:

    • Clinicians must maintain a high index of suspicion for TLS in surgical patients, especially with hematologic malignancies.
    • Perioperative TLS requires prompt recognition and aggressive management.
    • This case underscores the importance of vigilance for TLS outside of conventional chemotherapy settings.