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Published on: September 24, 2021
Pacemaker endocarditis: an important clinical entity
Kalpa De Silva1, Amanda Fife, Francis Murgatroyd
1St Thomas' Hospital, Department of Cardiology, Westminster Bridge Road, London SE1 7EH, UK.
Abstract:
Pacemaker endocarditis remains a rare but potentially life threatening complication of pacemaker implantation. This case illustrates a rare cause of pacemaker endocarditis, Serratia marcescens, the management difficulties that can be faced with such organisms, and the potential indolent nature of pacemaker lead associated endocarditis. A review of the current data for pacemaker endocarditis management suggests that treatment with antimicrobials alone is unlikely to be curative and explantation of the device is recommended in all cases of confirmed pacemaker endocarditis (by echocardiography, in correlation with the patient's clinical condition and inflammatory markers).
Insights
Pacemaker endocarditis, a rare complication, can be caused by Serratia marcescens. Device removal is recommended for confirmed cases, as antibiotics alone are often insufficient for treatment.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Device Complications
Background:
- Pacemaker endocarditis is a rare but serious complication following pacemaker implantation.
- Serratia marcescens represents an uncommon pathogen in pacemaker endocarditis.
- The indolent presentation of lead-associated endocarditis poses diagnostic challenges.
Purpose of the Study:
- To highlight Serratia marcescens as a rare cause of pacemaker endocarditis.
- To discuss the management complexities associated with this organism.
- To emphasize the importance of device explantation in confirmed cases.
Main Methods:
- Case illustration of pacemaker endocarditis.
- Review of current literature on pacemaker endocarditis management.
- Diagnostic correlation using echocardiography, clinical status, and inflammatory markers.
Main Results:
- Serratia marcescens can cause pacemaker endocarditis with potentially indolent progression.
- Antimicrobial therapy alone is generally inadequate for curative treatment.
- Confirmed pacemaker endocarditis necessitates device explantation.
Conclusions:
- Pacemaker endocarditis requires a comprehensive management approach.
- Early diagnosis and intervention, including device removal, are crucial.
- Serratia marcescens presents unique challenges in managing pacemaker endocarditis.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
Pericarditis II: Clinical Features and Diagnostic Tests
Pericarditis I: Introduction
