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Updated: May 27, 2026
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Percutaneous cryoablation of pulmonary metastases from colorectal cancer
Yoshikane Yamauchi1, Yotaro Izumi, Masafumi Kawamura
1Department of Surgery, School of Medicine, Keio University, Tokyo, Japan. yoshikaney@2004.jukuin.keio.ac.jp
Objective:
To evaluate the safety and efficacy of cryoablation for metastatic lung tumors from colorectal cancer.
Methods:
The procedures were performed on 24 patients (36-82 years of age, with a median age of 62; 17 male patients, 7 female patients) for 55 metastatic tumors in the lung, during 30 sessions. The procedural safety, local progression free interval, and overall survival were assessed by follow-up computed tomographic scanning performed every 3-4 months.
Results:
The major complications were pneumothorax, 19 sessions (63%), pleural effusion, 21 sessions (70%), transient and self-limiting hemoptysis, 13 sessions (43%) and tract seeding, 1 session (3%). The 1- and 3-year local progression free intervals were 90.8% and 59%, respectively. The 3-years local progression free intervals of tumors ≤15 mm in diameter was 79.8% and that of tumors >15 mm was 28.6% (p = 0.001; log-rank test). The 1- and 3-year overall survival rates were 91% and 59.6%, respectively.
Conclusion:
The results indicated that percutaneous cryoablation is a feasible treatment option. The local progression free interval was satisfactory at least for tumors that were ≤15 mm in diameter.
