Related Experiment Video
Updated: May 27, 2026

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
Published on: July 27, 2022
[Study on in vitro release of xingnaojing microemulsion]
Shan Wang1, Shouying Du, Yang Lu
1School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China. ant5wangshan@163.com
Objective:
To study in vitro release of Xingnaojing microemulsion and to investigate the release mechanism.
Method:
The concentration of jasminoidin was determined by HPLC and the concentration of Aipian was determined by GC. In vitro release characteristics were conducted by dialysis technique. Model fitting was used to determine the kinetics and mechanism.
Result:
Jasminoidin released completely within 2 h, fitting the Weibell model best. The release of borneol fitted first order model.
Conclusion:
The release mechanisms of different types of medicines are quite different. The different types of medicines dissolve in the different phases in the microemulsion.
Related Concept Videos
In Vitro Drug Dissolution: Alternative Methods
In Vitro Drug Release Testing: Overview, Development and Validation
In Vitro Drug Dissolution: Compendial Testing Models II
In Vitro Drug Dissolution: Compendial Testing Models I
Modified-Release Drug Delivery Systems: Bioavailability

