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Ultrastructural evidence for serotonin-immunoreactive terminals contacting phrenic motoneurons in the cat
J R Holtman1, D S Vascik, B E Maley
1Department of Pharmacology, College of Medicine, University of Kentucky, Lexington 40536.
Experimental Neurology
|September 1, 1990
Abstract:
The innervation of the phrenic motor nucleus in the cat by serotonin-containing neurons has been studied using retrograde tracing combined with immunohistochemistry at the electron microscope level. It was found that phrenic motoneuron cell bodies and dendrites are contacted by serotonin-immunoreactive synaptic terminals. This finding suggests that the activity of phrenic motoneurons is directly affected by serotonergic neurons.